Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842006 | 1.00 | CHRM3 (0.45) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL2519762 | 0.85 | MMP2 (0.41) | CHRM3LMNABLMCYP2D6CHRM2 | |
| SCHEMBL2512019 | 0.82 | CHRM3 (0.54) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL2482977 | 0.82 | CHRM3 (0.54) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL2990935 | 0.82 | CHRM3 (0.67) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL9667211 | 0.80 | CHRM3 (0.64) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL15000746 | 0.79 | MMP2 (0.47) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL17294713 | 0.79 | LMNA (0.59) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL17294710 | 0.79 | LMNA (0.59) | CHRM3LMNATHRBBLMPMP22 | |
| SCHEMBL2482540 | 0.78 | LMNA (0.67) | CHRM3LMNABLMPMP22CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206712-A1 | \"Alkaloid aminoester derivatives and medicinal composition thereof\ | CHIESI FARMACEUTICI S.p.A. (IT) | 2010-07-14 | — | — | EP | disclosed |