Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.75 |
| ▸ | RAB9A | P51151 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28565749 | 0.91 | MAPT (0.70) | MAPTRAB9AMEN1KMT2APKM | |
| Azobenzene SCHEMBL27839005 | 0.87 | ALDH1A1 (0.67) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL208183 | 0.87 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL15292217 | 0.87 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL29001131 | 0.87 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL208182 | 0.87 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL11794668 | 0.87 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL11794663 | 0.87 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL6123777 | 0.87 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL2382817 | 0.84 | MEN1 (0.95) | MAPTRAB9AMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106825591-A | A kind of tin alkene raw powder's production technology | 厦门圣之岛金属科技有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-104961113-B | A kind of method for preparing phosphorus alkene | 北京石油化工学院 | 2017-06-06 | — | — | CN | disclosed |