Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28128761 | 0.91 | MAPT (0.75) | MAPTTDP1RAB9AMEN1KMT2A | |
| SCHEMBL11329238 | 0.84 | MAPT (1.00) | MAPTTDP1RAB9AMEN1KMT2A | |
| Alcohol SCHEMBL10901320 | 0.84 | MEN1 (0.57) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL205992 | 0.84 | MAPT (1.00) | MAPTTDP1RAB9AMEN1KMT2A | |
| SCHEMBL11318226 | 0.84 | MAPT (1.00) | MAPTTDP1RAB9AMEN1KMT2A | |
| SCHEMBL11329248 | 0.84 | MAPT (1.00) | MAPTTDP1RAB9AMEN1KMT2A | |
| SCHEMBL16556 | 0.84 | MAPT (1.00) | MAPTTDP1RAB9AMEN1KMT2A | |
| SCHEMBL11329226 | 0.84 | MAPT (1.00) | MAPTTDP1RAB9AMEN1KMT2A | |
| Alcohol SCHEMBL28559934 | 0.83 | RAB9A (0.55) | MAPTTDP1RAB9AMEN1KMT2A | |
| SCHEMBL12653890 | 0.81 | MAPT (0.64) | MAPTTDP1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759777-B | Anti-ultraviolet self-repairing polymer and preparation method and application thereof | 山东师范大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112759777-A | Anti-ultraviolet self-repairing polymer and preparation method and application thereof | 山东师范大学 | 2021-05-07 | — | — | CN | disclosed |