Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403573 | 0.88 | SIGMAR1 (0.39) | ALDH1A1KDM4ETDP1L3MBTL1 | |
| Bromide SCHEMBL28938863 | 0.87 | SIGMAR1 (0.38) | ALDH1A1KDM4ETDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4647603 | 0.87 | SIGMAR1 (0.38) | ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL28987702 | 0.83 | PDE4A (0.40) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| Nitric Acid SCHEMBL27828030 | 0.78 | MAPT (0.40) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 | |
| Nitric Acid SCHEMBL28461800 | 0.76 | — | — | |
| Nitric Acid SCHEMBL28664481 | 0.76 | — | — | |
| SCHEMBL31263708 | 0.76 | NR1I2 (0.32) | KMT2A | |
| Nitric Acid SCHEMBL28402693 | 0.74 | APEX1 (0.36) | MEN1KMT2ACYP2C19CYP2D6LMNA | |
| SCHEMBL3781641 | 0.73 | MAPT (0.37) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106367170-B | Compound machine oil of the plant of containing graphene and preparation method thereof | 颜凤生 | 2019-10-01 | — | — | CN | claimed |
| CN-106367170-A | Plant composite engine oil containing graphene and preparation method thereof | 颜凤生 | 2017-02-01 | — | — | CN | claimed |
| CN-106367170-B | Compound machine oil of the plant of containing graphene and preparation method thereof | 颜凤生 | 2019-10-01 | — | — | CN | disclosed |
| CN-106367170-A | Plant composite engine oil containing graphene and preparation method thereof | 颜凤生 | 2017-02-01 | — | — | CN | disclosed |