Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 3/20 | 0.38 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.35 |
| ▸ | DRD4 known ✓ | P21917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403573 | 0.98 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1KDM4EL3MBTL1FUCA1 | |
| Bromide SCHEMBL28938863 | 0.97 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1KDM4EL3MBTL1FUCA1 | |
| Nitric Acid SCHEMBL28128886 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL28987702 | 0.87 | PDE4A (0.40) | ALDH1A1KDM4E | |
| SCHEMBL3781641 | 0.81 | MAPT (0.37) | ALDH1A1 | |
| SCHEMBL31263708 | 0.81 | NR1I2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL9343069 | 0.81 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1KDM4EL3MBTL1FUCA1 | |
| SCHEMBL1044027 | 0.79 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1KDM4EL3MBTL1FUCA1 | |
| SCHEMBL23619153 | 0.78 | POLB (0.38) | SIGMAR1TDP1 | |
| SCHEMBL1082728 | 0.77 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1L3MBTL1FUCA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294447-B1 | MOLECULARLY IMPRINTED POLYMERS | PHASE HOLOGRAPHIC IMAGING PHI AB (SE) | 2023-12-06 | — | — | EP | claimed |
| US-10730986-B2 | Molecularly imprinted polymers | PHASE HOLOGRAPHIC IMAGING PHI AB (SE) | 2020-08-04 | — | — | US | claimed |
| US-20180142053-A1 | MOLECULARLY IMPRINTED POLYMERS | BUNDESREPUBLIK DEUTSCHLAND, VERTRETEN DURCH DEN BUNDESMINISTER FÜR WIRTSCHAFT UND ENERGIE, DIESER VERTRETEN DURCH DEN PRÄSIDENTEN DER BUNDESANSTALT FÜR MATERIALFORSCHUNG - UND PRÜFUNG (DE) | 2018-05-24 | — | — | US | claimed |
| US-6503608-B2 | Loading printer with ink-receptive elements comprising a support having thereon an image-receiving layer comprising a support having an image-receiving layer comprising a cationic, water-dispersible, quaternized imidazole-containing polymer | EASTMAN KODAK COMPANY | 2003-01-07 | — | — | US | claimed |
| US-20020145635-A1 | Ink jet printing method | EASTMAN KODAK COMPANY | 2002-10-10 | — | — | US | claimed |
| EP-1226964-A2 | Ink jet printing method | EASTMAN KODAK COMPANY (US) | 2002-07-31 | — | — | EP | claimed |
| US-20250376638-A1 | HARD SURFACE CLEANING COMPOSITIONS COMPRISING ALKOXYLATED PHENOLS AND PERFUMES AND CLEANING PADS AND METHODS FOR USING SUCH CLEANING COMPOSITIONS | PROCTER & GAMBLE (US) | 2025-12-11 | — | — | US | disclosed |
| US-20240101934-A1 | HARD SURFACE CLEANING COMPOSITION AND METHOD OF IMPROVING SURFACE SHINE USING THE SAME | PROCTER & GAMBLE (US) | 2024-03-28 | — | — | US | disclosed |
| US-20240101935-A1 | HARD SURFACE CLEANING COMPOSITION AND METHOD OF IMPROVING SURFACE SHINE USING THE SAME | PROCTER & GAMBLE (US) | 2024-03-28 | — | — | US | disclosed |
| US-11859158-B2 | Hard surface cleaning composition and method of improving surface shine using the same | THE PROCTER & GAMBLE COMPANY (US) | 2024-01-02 | — | — | US | disclosed |
| EP-3294447-B1 | MOLECULARLY IMPRINTED POLYMERS | PHASE HOLOGRAPHIC IMAGING PHI AB (SE) | 2023-12-06 | — | — | EP | disclosed |
| CN-111961768-B | Preparation method of amphoteric polyacrylic acid retanning agent | 汤普勒新材料嘉兴有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-113583181-B | High-strength cation-pi-type aggregate binder and preparation method thereof | 华中科技大学 | 2022-05-20 | — | — | CN | disclosed |
| US-5942588-A | CONTAINING POLYMERIC PROTECTIVE COLLOID COMPRISING COPOLYMER OF N-VINYLPYRROLIDONE AND N-VINYLIMIDAZOLE | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-24 | — | — | US | disclosed |
| US-5846924-A | Use of vinylpyrrolidone and vinylimidazole copolymers as detergent additives, novel polymers of vinylpyrrolidone and of vinylimidazole, and preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5830844-A | WATER INSOLUBLE CROSSLINKED POLYMERS CONTAINING PYRROLIDONE AND IMIDAZOLE RINGS | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| US-5773545-A | Polymers of alkyl-1-vinylimidazloes, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| US-5677384-A | Grafted polyamidoamines and grafted polyethyleneimines, preparation thereof, and use thereof as detergent additives | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5627151-A | WASHING TEXTILES USING DYE TRANSFER INHIBITOR | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5622926-A | INHIBITING DYE TRANSFER | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730986-B2 | Molecularly imprinted polymers | SIGLEC7, CD44, MPI | SIGMAR1 3189/4885CHRM2 3131/4885CHRM4 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.