Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17072540 | 0.80 | HSD17B3 (0.58) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL9480411 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL3780427 | 0.76 | ALDH1A1 (0.53) | KDM4EAKR1B1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3784810 | 0.74 | ALDH1A1 (0.54) | KDM4EAKR1B1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6365673 | 0.72 | MCL1 (0.68) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL11827391 | 0.70 | PIM1 (0.53) | KDM4EALDH1A1KMT2ALMNACA12 | |
| SCHEMBL11308857 | 0.68 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL27903486 | 0.68 | ALDH1A1 (0.57) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| 4-Methylesculetin SCHEMBL29361762 | 0.67 | MCL1 (1.00) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| 4-Methylesculetin SCHEMBL409482 | 0.67 | MCL1 (1.00) | MCL1KDM4EAKR1B1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432369-B | Synthetic method of the one kind based on Indophenols, the glucosides of 2- (benzothiazole -2 '-yl) phenol derivatives | 广东省微生物研究所 | 2019-01-08 | — | — | CN | disclosed |
| CN-106432369-A | Synthesis method of glucoside based on indoxyl derivative and 2-(benzothiazol-2'-yl)phenol derivative | 广东省微生物研究所 | 2017-02-22 | — | — | CN | disclosed |