Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 5/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754925 | 0.80 | GSK3B (0.62) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL29864773 | 0.71 | GSK3B (0.50) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7736928 | 0.71 | GSK3B (0.50) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL135332 | 0.71 | GSK3B (0.56) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9016868 | 0.71 | GSK3B (0.50) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9561195 | 0.70 | GSK3B (0.54) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1499914 | 0.70 | GSK3B (0.54) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14763938 | 0.70 | GSK3B (0.54) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29032840 | 0.69 | GSK3B (0.54) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28821133 | 0.69 | GSK3B (0.54) | GSK3BKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078762-A | A method of preparing β-sulfydryl phosphono analog derivative | 苏州大学 | 2019-08-02 | — | — | CN | claimed |
| CN-106432329-B | A kind of beta-cyano phosphono analog derivative and the preparation method and application thereof | 苏州大学 | 2018-07-31 | — | — | CN | claimed |
| CN-107556340-A | β -thiocyano phosphonyl derivative and preparation method thereof | 苏州大学 | 2018-01-09 | — | — | CN | claimed |
| CN-107424916-A | Lightwave detector substrate and preparation method thereof | 苏州益可泰电子材料有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-106432329-A | Beta-cyano phosphoryl derivatives as well as preparation method and application thereof | 苏州大学 | 2017-02-22 | — | — | CN | claimed |
| CN-110105387-A | A method of preparing β-sulfonic group phosphono analog derivative | 苏州大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-110078762-A | A method of preparing β-sulfydryl phosphono analog derivative | 苏州大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-107556340-B | β -thiocyano phosphonyl derivative and preparation method thereof | 苏州大学 | 2019-06-25 | — | — | CN | disclosed |
| CN-106432329-B | A kind of beta-cyano phosphono analog derivative and the preparation method and application thereof | 苏州大学 | 2018-07-31 | — | — | CN | disclosed |
| CN-107556340-A | β -thiocyano phosphonyl derivative and preparation method thereof | 苏州大学 | 2018-01-09 | — | — | CN | disclosed |
| CN-107424916-A | Lightwave detector substrate and preparation method thereof | 苏州益可泰电子材料有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-106432329-A | Beta-cyano phosphoryl derivatives as well as preparation method and application thereof | 苏州大学 | 2017-02-22 | — | — | CN | disclosed |