Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 4/20 | 0.47 |
| ▸ | PARP1 | P09874 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.40 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135332 | 0.88 | GSK3B (0.56) | GSK3BTDP2PARP1KDM4EALDH1A1 | |
| SCHEMBL29652041 | 0.87 | TDP2 (0.64) | GSK3BTDP2KDM4EALDH1A1GAA | |
| SCHEMBL28709463 | 0.87 | TDP2 (0.64) | GSK3BTDP2KDM4EALDH1A1GAA | |
| SCHEMBL10947949 | 0.86 | PPOX (0.50) | GSK3BTDP2PARP1KDM4EALDH1A1 | |
| SCHEMBL29032840 | 0.86 | GSK3B (0.54) | GSK3BTDP2PARP1KDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28821133 | 0.86 | GSK3B (0.54) | GSK3BTDP2PARP1KDM4EALDH1A1 | |
| SCHEMBL16754925 | 0.84 | GSK3B (0.62) | GSK3BTDP2PARP1KDM4EALDH1A1 | |
| SCHEMBL5616554 | 0.80 | GSK3B (0.52) | GSK3BTDP2PARP1KDM4EALDH1A1 | |
| SCHEMBL16521612 | 0.79 | TDP2 (0.43) | GSK3BTDP2PARP1KDM4EALDH1A1 | |
| SCHEMBL9116090 | 0.79 | GSK3B (0.45) | GSK3BTDP2PARP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514813-A | AND ALKALI METAL PHENOLATE, HIGH DILUTION, PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0634437-A1 | Preparation of macrocyclic polyetherimide oligomers | GENERAL ELECTRIC COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |