Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264423 | 0.89 | ERN1 (0.43) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL18228878 | 0.82 | ADRA2A (0.46) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL7196588 | 0.79 | KDM4E (0.54) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL18654154 | 0.76 | KDM4E (0.50) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL2039527 | 0.76 | SMN1; SMN2 (0.62) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL24677590 | 0.76 | KDM4E (0.50) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL29496935 | 0.76 | SMN1; SMN2 (0.62) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL18976884 | 0.76 | KDM4E (0.50) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL27684365 | 0.73 | CYP1A2 (0.38) | ADRA1DADRA1AADRA1BKDM4ELMNA | |
| SCHEMBL1639618 | 0.73 | CYP1A2 (0.46) | ADRA1DADRA1AADRA1BKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459087-B | Process for the preparation of activated blood coagulation factor X (FXa) inhibitors | 第三共株式会社 | 2019-04-09 | — | — | CN | disclosed |
| CN-106459087-A | Process for the preparation of activated blood coagulation factor X (FXa) inhibitors | 第三共株式会社 | 2017-02-22 | — | — | CN | disclosed |