Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.38 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28128764 | 0.79 | SLC2A1 (0.54) | NAMPTALOX5ALDH1A1CASP1HSD17B10 | |
| SCHEMBL17184380 | 0.78 | NAMPT (0.62) | NAMPTGRM2ALDH1A1 | |
| SCHEMBL17184358 | 0.77 | NAMPT (0.61) | NAMPTALDH1A1LMNA | |
| SCHEMBL28319523 | 0.72 | MAPK14 (0.36) | NAMPTALOX5 | |
| SCHEMBL28840511 | 0.68 | KDM4E (0.40) | NAMPTALOX5ALDH1A1SLC2A1 | |
| SCHEMBL24459866 | 0.67 | GRM2 (0.56) | GRM2IDO1TDO2IDO2 | |
| SCHEMBL28175267 | 0.66 | MAOA (0.36) | LMNA | |
| SCHEMBL17184460 | 0.66 | NAMPT (1.00) | NAMPT | |
| SCHEMBL28813746 | 0.64 | GRM2 (0.66) | GRM2 | |
| SCHEMBL25009258 | 0.64 | MAPT (0.51) | ALDH1A1CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458934-B | Quinoxaline compounds and application thereof | 米伦纽姆医药公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-106458934-A | Quinoxaline compounds and uses thereof | 米伦纽姆医药公司 | 2017-02-22 | — | — | CN | disclosed |