Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.47 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17184380 | 0.82 | NAMPT (0.62) | NAMPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL17184358 | 0.79 | NAMPT (0.61) | NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28129294 | 0.79 | NAMPT (0.49) | SLC2A1NAMPTADORA2AADORA1SLC2A3 | |
| SCHEMBL29405271 | 0.71 | MAPK14 (0.81) | MAPK14ADORA2AMAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL71619 | 0.71 | MAPK14 (0.81) | MAPK14ADORA2AMAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL14511640 | 0.70 | ALOX5 (0.51) | SLC2A1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL17718852 | 0.70 | SLC2A1 (1.00) | SLC2A1SLC2A3SLC2A4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7694431 | 0.70 | ALDH1A1 (0.59) | HSD17B10HPGDALDH1A1CYP2A13 | |
| SCHEMBL29767839 | 0.69 | MAPK14 (0.78) | MAPK14ADORA2AMAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL27962380 | 0.69 | MAPK14 (0.78) | MAPK14ADORA2AMAPK10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458934-B | Quinoxaline compounds and application thereof | 米伦纽姆医药公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-106458934-A | Quinoxaline compounds and uses thereof | 米伦纽姆医药公司 | 2017-02-22 | — | — | CN | disclosed |