Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28485520 | 0.98 | TP53 (0.41) | TP53MEN1KMT2AALDH1A1GLA | |
| SCHEMBL28128801 | 0.83 | MEN1 (0.46) | TP53MEN1KMT2AALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL28169815 | 0.81 | MEN1 (0.45) | TP53MEN1KMT2AALDH1A1GLA | |
| SCHEMBL4097943 | 0.78 | KMT2A (0.53) | TP53MEN1KMT2AALDH1A1GLA | |
| SCHEMBL837036 | 0.76 | NPC1 (0.47) | TP53ALDH1A1NPC1JAK2RAB9A | |
| SCHEMBL837432 | 0.74 | MEN1 (0.45) | TP53MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7009170 | 0.74 | NPC1 (0.44) | TP53MEN1KMT2AALDH1A1GLA | |
| SCHEMBL9340745 | 0.73 | TP53 (0.54) | TP53MEN1KMT2AALDH1A1GLA | |
| SCHEMBL10728982 | 0.73 | L3MBTL1 (0.49) | TP53MEN1KMT2AALDH1A1GLA | |
| SCHEMBL10824119 | 0.73 | MEN1 (0.53) | TP53MEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | disclosed |