Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 9/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114840 | 0.79 | NAAA (0.40) | MBOAT4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21081076 | 0.78 | DRD1 (0.49) | DRD1ALKBH1MRGPRX4NPC1RAB9A | |
| SCHEMBL28818088 | 0.76 | DAO (0.32) | — | |
| SCHEMBL29974801 | 0.75 | MBOAT4 (0.42) | MBOAT4HCRTR1HCRTR2DRD1RXRA | |
| SCHEMBL19555693 | 0.75 | MBOAT4 (0.45) | MBOAT4HCRTR1HCRTR2DRD1RXRA | |
| SCHEMBL4535683 | 0.75 | MBOAT4 (0.42) | MBOAT4HCRTR1HCRTR2DRD1RXRA | |
| SCHEMBL18378650 | 0.75 | MBOAT4 (0.45) | MBOAT4HCRTR1HCRTR2RXRAGRIN1 | |
| SCHEMBL2895609 | 0.75 | MBOAT4 (0.42) | MBOAT4HCRTR1HCRTR2RXRAGRIN1 | |
| SCHEMBL28088981 | 0.74 | BRD4 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL30106088 | 0.73 | ATM (0.44) | MBOAT4HCRTR1HCRTR2ALKBH1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459088-A | 2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8h)-yl-1,3-thiazol-4-yl amides | 辉瑞公司 | 2017-02-22 | — | — | CN | disclosed |