Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552151 | 0.95 | NOTUM (0.63) | NOTUMHTR2AHTR2CLMNANR3C1 | |
| SCHEMBL7382818 | 0.91 | NOTUM (0.62) | NOTUMHTR2AHTR2CLMNANR3C1 | |
| SCHEMBL30681440 | 0.86 | NOTUM (0.76) | NOTUMHTR2AHTR2CLMNACYP2C9 | |
| SCHEMBL27544652 | 0.83 | CNR2 (0.53) | NOTUMHTR2AHTR2CRAB9AHDAC1 | |
| SCHEMBL24011079 | 0.82 | NOTUM (0.84) | NOTUMLMNAMAPTL3MBTL1HTT | |
| SCHEMBL3653813 | 0.79 | NOTUM (0.61) | NOTUMHTR2AHTR2CLMNAKDM4E | |
| SCHEMBL26763830 | 0.79 | NOTUM (0.61) | NOTUMHTR2AHTR2CLMNANR3C1 | |
| SCHEMBL5696394 | 0.77 | NOTUM (0.59) | NOTUMHTR2AHTR2CLMNANR3C1 | |
| SCHEMBL6752845 | 0.77 | NOTUM (0.59) | NOTUMHTR2AHTR2CLMNANR3C1 | |
| SCHEMBL30767099 | 0.77 | NOTUM (0.59) | NOTUMHTR2AHTR2CLMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456539-A | pharmaceutical compositions of hydrophobic compounds | 阿森迪亚制药有限责任公司 | 2017-02-22 | — | — | CN | disclosed |