Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL28129644

C=CC(=O)OC.CN1C(=O)C=CC1=O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.50
GSK3B P49841 2/20 0.50
MGLL Q99685 1/20 0.50
NFE2L2 Q16236 4/20 0.36
HCAR2 Q8TDS4 2/20 0.34
KEAP1 Q14145 1/20 0.34
TGM2 P21980 1/20 0.33
THRB P10828 1/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32
HIF1A Q16665 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TYR P14679 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28213120 0.80 TSHR (0.35) NFE2L2HCAR2KEAP1TGM2TSHR
Acrylic Acid SCHEMBL28866175 0.79 MGLL (0.59) GSK3AGSK3BMGLLNFE2L2KEAP1
Benzoquinone SCHEMBL28170850 0.79 HCAR2 (0.40) NFE2L2HCAR2KEAP1TGM2THRB
Acrylic Acid Methyl Ester SCHEMBL17534933 0.76 MGLL (0.56) MGLLALDH1A1HPGDMAPTHTT
Acrylic Acid Methyl Ester SCHEMBL9108 0.76
Acrylic Acid Methyl Ester SCHEMBL1854813 0.76 HCAR2 (0.56) NFE2L2HCAR2KEAP1TGM2ALDH1A1
Acrylic Acid Methyl Ester SCHEMBL7645157 0.76 HCAR2 (0.56) NFE2L2HCAR2KEAP1TGM2ALDH1A1
Acrylic Acid Methyl Ester SCHEMBL4463613 0.74 GSK3A (0.44) GSK3AGSK3BNFE2L2HCAR2KEAP1
Maleic Anhydride SCHEMBL2034123 0.74 HCAR2 (0.36) NFE2L2HCAR2KEAP1TGM2THRB
Acrylic Acid Methyl Ester SCHEMBL7194299 0.74 HCAR2 (0.48) NFE2L2HCAR2KEAP1TGM2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459553-A Polycarbonate resin composition and article molded therefrom 三菱瓦斯化学株式会社 2017-02-22 CN disclosed