Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129661 | 1.00 | FOLH1 (0.47) | FOLH1CPA3NR4A2KMT2AHSD17B10 | |
| SCHEMBL27805530 | 0.88 | TRPM8 (0.44) | FOLH1CPA3NR4A2KMT2AHSD17B10 | |
| SCHEMBL11180508 | 0.86 | FOLH1 (0.40) | FOLH1LMNANPC1MAPTRAB9A | |
| SCHEMBL11180502 | 0.86 | FOLH1 (0.40) | FOLH1LMNANPC1MAPTRAB9A | |
| SCHEMBL28046659 | 0.84 | KMT2A (0.40) | FOLH1CPA3KMT2AHSD17B10TDP1 | |
| SCHEMBL27372764 | 0.84 | NPC1 (0.44) | FOLH1KMT2AMAPK1MEN1NPC1 | |
| SCHEMBL15905074 | 0.83 | FOLH1 (0.38) | FOLH1HDAC6 | |
| SCHEMBL27871867 | 0.81 | KMT2A (0.44) | FOLH1KMT2AMAPK1MEN1NPC1 | |
| SCHEMBL27871864 | 0.81 | KMT2A (0.44) | FOLH1KMT2AMAPK1MEN1NPC1 | |
| SCHEMBL12983595 | 0.81 | KMT2A (0.44) | FOLH1KMT2AMAPK1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432188-A | Preparation method of anti-cancer drug 2-[4-((3S)-3-Piperidinyl) phenyl]-2H-Indazole-7-Formamide | 青岛辰达生物科技有限公司 | 2017-02-22 | — | — | CN | claimed |