Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19961 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL27719143 | 0.88 | MAPT (0.46) | MAPTRAB9AHPGDKMT2ALMNA | |
| SCHEMBL27638023 | 0.88 | MAPT (0.46) | MAPTRAB9AHPGDKMT2ALMNA | |
| SCHEMBL28129844 | 0.86 | MAPT (0.41) | MAPTRAB9AHPGDKMT2ALMNA | |
| SCHEMBL28129858 | 0.86 | MAPT (0.41) | MAPTRAB9AHPGDKMT2ALMNA | |
| SCHEMBL28102945 | 0.80 | MAOB (0.43) | MAPTRAB9AHPGDKMT2ALMNA | |
| SCHEMBL455038 | 0.77 | HSD17B1 (0.61) | MAPTRAB9AHPGDKMT2ALMNA | |
| Zinc Chloride SCHEMBL28130449 | 0.77 | PGR (0.37) | — | |
| Zinc Chloride SCHEMBL28130452 | 0.77 | SMN1; SMN2 (0.46) | MAPTRAB9AHPGDKMT2AL3MBTL1 | |
| SCHEMBL28249450 | 0.76 | SMN1; SMN2 (0.59) | MAPTRAB9AHPGDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414388-A | Process for the manufacture of terphenyl compounds | 索尔维特殊聚合物美国有限责任公司 | 2017-02-15 | — | — | CN | claimed |
| CN-106414388-A | Process for the manufacture of terphenyl compounds | 索尔维特殊聚合物美国有限责任公司 | 2017-02-15 | — | — | CN | disclosed |