Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448097 | 0.83 | BCL2 (0.45) | BCL2BCL2L1PTPN1DAOHTR2A | |
| SCHEMBL28131365 | 0.79 | MAPT (0.34) | DAOL3MBTL1ELANECTSG | |
| SCHEMBL8056668 | 0.74 | BCL2 (0.53) | BCL2BCL2L1PTPN1HTR2AELANE | |
| SCHEMBL50088 | 0.72 | HTR2A (0.42) | BCL2BCL2L1PTPN1DAOHTR2A | |
| SCHEMBL27956681 | 0.71 | ESR1 (0.35) | PTPN1TSHRCALM1 | |
| SCHEMBL27956686 | 0.71 | HTT (0.34) | PTPN1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9763812 | 0.69 | HPGD (0.45) | BCL2BCL2L1HTR2AL3MBTL1TSHR | |
| SCHEMBL28131358 | 0.69 | GABRA1 (0.38) | TSHRCYP1A2CYP3A4 | |
| Oxirane SCHEMBL28356875 | 0.68 | BCL2 (0.46) | BCL2BCL2L1PTPN1HTR2AELANE | |
| SCHEMBL3853253 | 0.68 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980306-B | Preparation method for hypophosphorous acid / phosphorous acid/ phosphate compounds by adopting P(O)-OH-contained compounds | 湖南大学 | 2017-02-15 | — | — | CN | disclosed |