Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28130810 | 0.82 | TLR2 (0.35) | TLR2SMYD3 | |
| SCHEMBL8649429 | 0.80 | GRIK1 (0.35) | GRIK1GRIK2 | |
| SCHEMBL4959891 | 0.78 | BACE1 (0.34) | GRIK1GRIK2 | |
| SCHEMBL11824195 | 0.74 | EP300 (0.43) | GRIK1EP300 | |
| SCHEMBL11824178 | 0.74 | EP300 (0.43) | GRIK1EP300 | |
| SCHEMBL10474940 | 0.72 | GRIK1 (0.33) | GRIK1GRIK2EP300 | |
| SCHEMBL692341 | 0.72 | NAAA (0.42) | GRIK1EP300 | |
| SCHEMBL3010695 | 0.72 | NAAA (0.36) | GRIK1GRIK2EP300 | |
| SCHEMBL8645025 | 0.71 | GRIK1 (0.38) | GRIK1EP300 | |
| SCHEMBL990465 | 0.68 | CES2 (0.36) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565510-A | Preparation method for trans 4-amino-cyclohexyl acetate derivative | 浙江京新药业股份有限公司 | 2017-04-19 | — | — | CN | disclosed |