Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000749 | 0.92 | NPSR1 (0.36) | NPSR1FFAR4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28130276 | 0.91 | RAPGEF4 (0.37) | NPSR1FFAR4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28000756 | 0.82 | HTT (0.37) | NPSR1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL27975932 | 0.82 | NPSR1 (0.37) | NPSR1FFAR4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28131014 | 0.81 | HTT (0.45) | NPSR1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL28130275 | 0.81 | MEN1 (0.35) | NPSR1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL19367695 | 0.77 | RAPGEF4 (0.55) | FFAR4RAPGEF4ALDH1A1 | |
| SCHEMBL27975930 | 0.76 | ELANE (0.34) | NPSR1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12269615 | 0.76 | NPSR1 (0.44) | NPSR1FFAR4SMN1; SMN2RAPGEF4LMNA | |
| SCHEMBL19367690 | 0.76 | FFAR4 (0.47) | NPSR1FFAR4MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104250270-B | Asymmetric benzhydryl alpha-diimine nickel complex and preparation and application thereof | 中国石油天然气股份有限公司 | 2017-02-15 | — | — | CN | disclosed |