Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 14/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424941 | 0.84 | RAPGEF4 (0.55) | RAPGEF4FFAR4ALDH1A1 | |
| SCHEMBL14587753 | 0.84 | RAPGEF4 (0.55) | RAPGEF4FFAR4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1013011 | 0.82 | RAPGEF4 (0.52) | RAPGEF4FFAR4ALDH1A1 | |
| Bromide SCHEMBL28294732 | 0.82 | RAPGEF4 (0.52) | RAPGEF4FFAR4ALDH1A1 | |
| SCHEMBL2354467 | 0.80 | RAPGEF4 (0.50) | RAPGEF4FFAR4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29113098 | 0.78 | RAPGEF4 (0.48) | RAPGEF4FFAR4ALDH1A1 | |
| SCHEMBL28131012 | 0.77 | NPSR1 (0.39) | RAPGEF4FFAR4ALDH1A1 | |
| SCHEMBL29113095 | 0.75 | RAPGEF4 (0.44) | RAPGEF4FFAR4ALDH1A1 | |
| SCHEMBL11174052 | 0.74 | CYP1A2 (0.39) | ALDH1A1 | |
| SCHEMBL11170832 | 0.74 | CYP1A2 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267707-A1 | Methods and Compositions for Substituted Alpha-Aminophosphonate Analogues | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267707-A1 | Methods and Compositions for Substituted Alpha-Aminophosphonate Analogues | NPEPPS, AGPS, PHOSPHO1 | RAPGEF4 1274/4885FFAR4 2976/4885ALDH1A1 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.