Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067346 | 0.86 | HTT (0.62) | GFERMAPTPOLBHTTEGFR | |
| SCHEMBL28268479 | 0.84 | MAPT (0.50) | MAPTPOLBHTTEGFRHSD17B10 | |
| SCHEMBL5234885 | 0.82 | SMN1; SMN2 (0.52) | GFERMAPTPOLBHTTEGFR | |
| SCHEMBL28131223 | 0.81 | POLB (0.47) | MAPTPOLBHTTEGFRHSD17B10 | |
| SCHEMBL6671401 | 0.77 | EGFR (0.66) | MAPTHTTEGFRHSD17B10KDM4E | |
| SCHEMBL29414698 | 0.77 | EGFR (0.66) | MAPTHTTEGFRHSD17B10KDM4E | |
| SCHEMBL21782165 | 0.74 | RAB9A (0.55) | GFERMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28868911 | 0.74 | SRC (0.46) | MAPTPOLBHTTEGFRHSD17B10 | |
| SCHEMBL24067320 | 0.74 | EGFR (0.51) | GFERMAPTPOLBHTTEGFR | |
| SCHEMBL10085033 | 0.74 | MAPT (0.47) | MAPTPOLBHTTEGFRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459030-B | Replace tropane derivatives | 东亚荣养株式会社 | 2019-01-29 | — | — | CN | disclosed |
| CN-106459030-A | Substituted tropane derivatives | 东亚荣养株式会社 | 2017-02-22 | — | — | CN | disclosed |