Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.66 |
| ▸ | SRC | P12931 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671401 | 1.00 | EGFR (0.66) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL30002195 | 0.88 | KDM4E (0.61) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL984736 | 0.84 | EGFR (0.65) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL30443220 | 0.84 | EGFR (0.65) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL7278316 | 0.84 | EGFR (0.65) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL9959370 | 0.82 | KMT2A (0.56) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL28295413 | 0.81 | GAA (0.55) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL8999049 | 0.81 | EGFR (0.69) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL8702816 | 0.81 | KMT2A (0.62) | EGFRSRCKMT2AALDH1A1KDM4E | |
| SCHEMBL28068134 | 0.81 | EGFR (0.64) | EGFRSRCKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| EP-3965884-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |