Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829248 | 0.84 | ACHE (0.55) | BCHEMGLL | |
| Benzoic Acid SCHEMBL11280430 | 0.78 | NAAA (0.60) | NAAASMN1; SMN2TSHRHTTCYP2C9 | |
| SCHEMBL11280450 | 0.77 | BCHE (0.57) | BCHENAAASMN1; SMN2TSHRHTT | |
| Benzoic Acid SCHEMBL5862551 | 0.74 | NAAA (0.54) | NAAASMN1; SMN2TSHRHTT | |
| Benzoic Acid SCHEMBL27413851 | 0.72 | TSHR (0.67) | NAAATSHR | |
| Benzoic Acid SCHEMBL6573567 | 0.72 | TSHR (0.67) | NAAATSHR | |
| Benzoic Acid SCHEMBL28845500 | 0.72 | TSHR (0.67) | NAAATSHR | |
| Benzoic Acid SCHEMBL9594281 | 0.72 | TSHR (0.67) | NAAATSHR | |
| Benzoic Acid SCHEMBL9157936 | 0.72 | TSHR (0.67) | NAAATSHR | |
| SCHEMBL8341949 | 0.71 | ACHE (0.53) | BCHENAAASMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220043-B | Foaming formulations and cleaning products comprising silicone polyesters | 金伯利-克拉克环球有限公司 | 2017-03-01 | — | — | CN | disclosed |