SCHEMBL28132018

SCHEMBL28132018

CC(C#N)c1nc(-c2ccccc2)[nH]c1CCC#N

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
PIN1 Q13526 1/20 0.35
GRIN2B Q13224 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LTB4R Q15722 1/20 0.34
PDE5A O76074 1/20 0.34
PDE3B Q13370 1/20 0.34
PDE3A Q14432 1/20 0.34
HTT P42858 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10929550 0.79 KDM4E (0.41) HPGDALDH1A1CYP1A2CYP2C9PIN1
SCHEMBL31474430 0.79 HPGD (0.35) HPGDALDH1A1CYP1A2CYP2C9PIN1
SCHEMBL29225415 0.75
SCHEMBL28360708 0.74 LTB4R (0.42) HPGDALDH1A1CYP1A2CYP2C9PIN1
SCHEMBL10824694 0.69 LTB4R (0.33) HPGDALDH1A1CYP1A2CYP2C9MEN1
SCHEMBL10731037 0.69 GAA (0.41) HPGDALDH1A1CYP1A2CYP2C9PIN1
SCHEMBL29149618 0.68 MEN1 (0.32) MEN1KMT2A
Mefenidil SCHEMBL122152 0.67 KDM4E (0.43) HPGDALDH1A1CYP1A2CYP2C9PIN1
SCHEMBL13115345 0.66 MAPK14 (0.50) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL29129799 0.65 SCN2A (0.49) PIN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543941-A Automobile epoxy bond compositionss and the adhesive method using this (株)利来化学商社 2017-03-29 CN disclosed