SCHEMBL28360708

SCHEMBL28360708

N#CCCc1[nH]c(-c2ccccc2)nc1Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.42
ALDH1A1 P00352 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP2C9 P11712 3/20 0.38
HPGD P15428 3/20 0.38
CYP1A2 P05177 2/20 0.38
GAA P10253 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
MAPK13 O15264 1/20 0.33
RAF1 P04049 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10727938 0.81 LTB4R (0.61) LTB4RALDH1A1MEN1KMT2ACYP2C9
SCHEMBL4879388 0.81 LTB4R (0.45) LTB4RALDH1A1CYP2C9HPGDCYP1A2
SCHEMBL10929550 0.79 KDM4E (0.41) ALDH1A1MEN1KMT2ACYP2C9HPGD
SCHEMBL468691 0.77 LTB4R (0.47) LTB4RALDH1A1CYP2C9HPGDCYP1A2
SCHEMBL13115345 0.74 MAPK14 (0.50) MEN1KMT2AKDM4ENPC1RAB9A
SCHEMBL28132018 0.74 HPGD (0.35) LTB4RALDH1A1MEN1KMT2ACYP2C9
SCHEMBL31474430 0.74 HPGD (0.35) LTB4RALDH1A1MEN1KMT2ACYP2C9
SCHEMBL11396560 0.74 LTB4R (0.44) LTB4RALDH1A1HPGDCYP1A2GAA
SCHEMBL8764478 0.72 PIN1 (0.50) LTB4RALDH1A1CYP2C9HPGDCYP1A2
SCHEMBL16412171 0.71 KDM4E (0.42) LTB4RALDH1A1GAAKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110804412-A High-frequency low-loss insulating adhesive film material and preparation method thereof 中国科学院深圳先进技术研究院 2020-02-18 CN disclosed