SCHEMBL28132166

SCHEMBL28132166

C=CCC.CCCCCCCCCC[Si](OC)(OC)OCOCCCCC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.32
PLA2G2C Q5R387 1/20 0.32
LPAR1 Q92633 5/20 0.31
LPAR3 Q9UBY5 5/20 0.31
LPAR6 P43657 3/20 0.31
LPAR4 Q99677 3/20 0.31
LPAR5 Q9H1C0 3/20 0.31
LPAR2 Q9HBW0 3/20 0.31
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23114238 0.92 LMNA (0.33) LMNAMEN1THRBHTTKMT2A
SCHEMBL28281081 0.91 LMNA (0.44) LMNAMEN1THRBHTTKMT2A
SCHEMBL28101376 0.91 LMNA (0.44) LMNAMEN1THRBHTTKMT2A
SCHEMBL28853041 0.91 LMNA (0.44) LMNAMEN1THRBHTTKMT2A
SCHEMBL28875104 0.91 LMNA (0.44) LMNAMEN1THRBHTTKMT2A
SCHEMBL28135824 0.91 LMNA (0.44) LMNAMEN1THRBHTTKMT2A
SCHEMBL28292940 0.88 LMNA (0.40) LMNAMEN1THRBHTTKMT2A
SCHEMBL28201314 0.85 LMNA (0.42) LMNAMEN1THRBHTTKMT2A
SCHEMBL15190614 0.84 LMNA (0.40) LMNATSHR
Propene SCHEMBL1133857 0.84 LMNA (0.33) LMNAMEN1THRBHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103980911-B Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal display cells and its manufacture method JSR株式会社 2017-03-01 CN disclosed