SCHEMBL28292940

SCHEMBL28292940

CC=CC.CCCCCCCC[Si](OC)(OC)OCOCCCCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
THRB P10828 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
LPAR3 Q9UBY5 7/20 0.33
LPAR1 Q92633 5/20 0.33
LPAR2 Q9HBW0 5/20 0.33
LPAR6 P43657 3/20 0.33
LPAR4 Q99677 3/20 0.33
LPAR5 Q9H1C0 3/20 0.33
CES2 O00748 2/20 0.33
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
USP2 O75604 1/20 0.31
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28875104 0.93 LMNA (0.44) LMNAHTTMEN1THRBKMT2A
SCHEMBL28853041 0.93 LMNA (0.44) LMNAHTTMEN1THRBKMT2A
SCHEMBL28135824 0.93 LMNA (0.44) LMNAHTTMEN1THRBKMT2A
SCHEMBL28101376 0.93 LMNA (0.44) LMNAHTTMEN1THRBKMT2A
SCHEMBL28281081 0.93 LMNA (0.44) LMNAHTTMEN1THRBKMT2A
SCHEMBL1133938 0.92 LMNA (0.34) LMNAHTTMEN1THRBKMT2A
SCHEMBL28201314 0.88 LMNA (0.42) LMNAHTTMEN1THRBKMT2A
SCHEMBL28132166 0.88 LMNA (0.38) LMNAHTTMEN1THRBKMT2A
SCHEMBL28641894 0.86 LMNA (0.41) LMNAHTTMEN1THRBKMT2A
SCHEMBL27607404 0.84 LMNA (0.38) LMNAHTTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104610877-B The product of coating composition and coating containing titanium oxide 信越化学工业株式会社 2019-04-23 CN disclosed