Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694256 | 0.72 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2KDM4ETSHRL3MBTL1 | |
| SCHEMBL28343693 | 0.70 | L3MBTL1 (0.53) | ALDH1A1SMN1; SMN2TSHRL3MBTL1MAPT | |
| SCHEMBL29093421 | 0.70 | BTK (0.44) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1MAPT | |
| SCHEMBL4706518 | 0.69 | — | — | |
| SCHEMBL29830938 | 0.68 | L3MBTL1 (0.59) | ALDH1A1SMN1; SMN2TSHRL3MBTL1MAPT | |
| SCHEMBL41191 | 0.68 | L3MBTL1 (0.59) | ALDH1A1SMN1; SMN2TSHRL3MBTL1MAPT | |
| SCHEMBL5183283 | 0.68 | — | — | |
| SCHEMBL22788413 | 0.67 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KDM4ETSHRL3MBTL1 | |
| SCHEMBL29985764 | 0.67 | L3MBTL1 (0.66) | ALDH1A1SMN1; SMN2L3MBTL1MAPTHRH3 | |
| SCHEMBL31276017 | 0.67 | L3MBTL1 (0.66) | ALDH1A1L3MBTL1HRH3HRH4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749268-A | Heteroaryl compound and its application in medicine | 广东东阳光药业有限公司 | 2017-05-31 | — | — | CN | disclosed |