Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | ARG1 | P05089 | 4/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447008 | 1.00 | FDPS (0.41) | FDPSARG1ARG2NOS2NOS3 | |
| SCHEMBL10098487 | 1.00 | FDPS (0.41) | FDPSARG1ARG2NOS2NOS3 | |
| SCHEMBL19124799 | 0.94 | FDPS (0.47) | FDPSARG1ARG2CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL6988735 | 0.92 | FDPS (0.46) | FDPSARG1ARG2CYP2D6MEN1 | |
| SCHEMBL5389839 | 0.90 | FDPS (0.40) | FDPSARG1ARG2NOS2NOS3 | |
| Trifluoroacetic Acid SCHEMBL13732304 | 0.88 | CHRNB2 (0.38) | FDPSARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL28215603 | 0.88 | CHRNB2 (0.38) | FDPSARG1ARG2 | |
| SCHEMBL8695810 | 0.85 | — | — | |
| SCHEMBL4778976 | 0.82 | FDPS (0.42) | FDPSARG1ARG2CYP2D6MEN1 | |
| SCHEMBL6642206 | 0.82 | FDPS (0.42) | FDPSARG1ARG2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416229-B | Cytotoxic and antimitotic compounds and methods of use thereof | 酵活英属哥伦比亚有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-106470708-A | Antibody-drug-conjugates and their use for the treatment of cancer | 皮埃尔法布雷医药公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-106456800-A | IGF-1R antibody-drug-conjugates and uses thereof for the treatment of cancer | 皮埃尔法布雷医药公司 | 2017-02-22 | — | — | CN | disclosed |