Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL10934156 | 0.89 | — | — | |
| Glycine SCHEMBL28823271 | 0.84 | GLRA1 (0.56) | GLRA1SLC6A9OR51E2GABRR1CYP1A2 | |
| Glycine SCHEMBL30844145 | 0.84 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2GABRR1CYP1A2 | |
| Glycine SCHEMBL456097 | 0.84 | — | — | |
| Glycine SCHEMBL28363644 | 0.81 | — | — | |
| Formic Acid SCHEMBL27849088 | 0.81 | — | — | |
| Glycine SCHEMBL22206093 | 0.78 | — | — | |
| Glycine SCHEMBL7618266 | 0.76 | OR51E2 (0.59) | GLRA1SLC6A9OR51E2GABRR1CYP1A2 | |
| Malonic Acid SCHEMBL8976510 | 0.73 | LDHA (0.56) | GLRA1SLC6A9OR51E2CYP1A2 | |
| Glycine SCHEMBL28314139 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432836-A | Anti-aging rubber sealing piece and preparation method thereof | 青岛海之源智能技术有限公司 | 2017-02-22 | — | — | CN | disclosed |