Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28127594 | 1.00 | USP2 (0.42) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL13073441 | 0.85 | USP2 (0.39) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL27752719 | 0.85 | USP2 (0.41) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL2561810 | 0.85 | USP2 (0.41) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL19051326 | 0.84 | USP2 (0.40) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL1005678 | 0.83 | USP2 (0.44) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL1005680 | 0.83 | USP2 (0.44) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL105348 | 0.82 | NR1H2 (0.47) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL16018 | 0.82 | NR1H2 (0.47) | USP2SMN1; SMN2NR1H2MAPK1MAPT | |
| SCHEMBL16843 | 0.82 | NR1H2 (0.47) | USP2SMN1; SMN2NR1H2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573928-A | 2-aminothiazole derivative or salt thereof | 安斯泰来制药株式会社 | 2017-04-19 | — | — | CN | disclosed |