Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306402 | 0.89 | FOLH1 (0.66) | FOLH1TSHRALDH1A1ALOX15HMGB1 | |
| Hydrochloric Acid SCHEMBL10627695 | 0.88 | FOLH1 (0.63) | FOLH1TSHRALDH1A1ALOX15HMGB1 | |
| Furan SCHEMBL28455367 | 0.81 | CLCN2 (0.50) | FOLH1TSHRALDH1A1ALOX15HMGB1 | |
| SCHEMBL8791639 | 0.79 | FOLH1 (0.61) | FOLH1TSHRALDH1A1ALOX15HMGB1 | |
| Phthalic Acid SCHEMBL27844410 | 0.78 | ALDH1A1 (0.70) | ALDH1A1ALOX15HMGB1CYP1A2 | |
| Phthalic Acid SCHEMBL27844411 | 0.78 | ALDH1A1 (0.70) | ALDH1A1ALOX15HMGB1CYP1A2 | |
| SCHEMBL70392 | 0.78 | FOLH1 (0.76) | FOLH1TSHRALDH1A1ALOX15HMGB1 | |
| SCHEMBL30365583 | 0.78 | FOLH1 (0.76) | FOLH1TSHRALDH1A1ALOX15HMGB1 | |
| SCHEMBL9615025 | 0.78 | LMNA (0.60) | FOLH1TSHRALDH1A1ALOX15SLC16A3 | |
| SCHEMBL27773761 | 0.76 | FOLH1 (0.47) | FOLH1TSHRALDH1A1ALOX15HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928247-A | Spiral shell oxindole compounds and its purposes as therapeutic agent | 泽农医药公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-103664973-B | Spiro-oxindole compounds and their use as therapeutic agents | 泽农医药公司 | 2017-04-19 | — | — | CN | disclosed |