SCHEMBL28136192

SCHEMBL28136192

Cc1cc2c(cc1C)COCC2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PIR O00625 1/20 0.32
PIK3CD O00329 1/20 0.31
BTK Q06187 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24869682 0.82 CYP3A4 (0.38) PIK3CD
SCHEMBL22271439 0.82 PRKCG (0.37)
SCHEMBL13822493 0.78 GRIN2D (0.33)
SCHEMBL16744203 0.76 MAPT (0.31)
SCHEMBL22792436 0.76 KDM4E (0.30)
SCHEMBL8237889 0.76 PIK3CD (0.36) PIRPIK3CDBTK
SCHEMBL29596569 0.76 CYP3A4 (0.48)
SCHEMBL3499450 0.76 METAP1 (0.35) PIK3CD
SCHEMBL29853819 0.73 MEN1 (0.39) PIK3CD
SCHEMBL11340672 0.73 CHRNA7 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106660982-A Histone demethylase inhibitors 赛尔基因昆蒂赛尔研究公司 2017-05-10 CN disclosed