Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PIR | O00625 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499450 | 0.92 | METAP1 (0.35) | PIK3CDMETAP1ADRA2APARP10PARP11 | |
| SCHEMBL30743772 | 0.82 | IKBKB (0.41) | METAP1PARP10PARP11PARP1ALDH1A1 | |
| SCHEMBL3896106 | 0.82 | IKBKB (0.41) | METAP1PARP10PARP11PARP1ALDH1A1 | |
| SCHEMBL19835496 | 0.80 | METAP1 (0.37) | METAP1PARP10PARP11PARP1ALDH1A1 | |
| SCHEMBL19810444 | 0.76 | PARP10 (0.44) | METAP1PARP10PARP11PARP1ALDH1A1 | |
| SCHEMBL19836066 | 0.76 | PARP10 (0.37) | METAP1PARP10PARP11PARP1ACHE | |
| SCHEMBL28136192 | 0.76 | PIR (0.32) | PIK3CDPIRBTK | |
| SCHEMBL19023151 | 0.75 | DRD2 (0.43) | — | |
| SCHEMBL4523516 | 0.75 | PNMT (0.46) | PIK3CDMETAP1ADRA2APARP10PARP11 | |
| SCHEMBL9122886 | 0.75 | CA1 (0.39) | PIK3CDPARP10PARP1RAB9ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014859-A | Triazole indolol compound and synthesis method thereof | 绍兴文理学院 | 2022-02-08 | — | — | CN | claimed |
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | LIFEARC (GB) | 2024-06-27 | — | — | US | disclosed |
| WO-2023141323-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-3582783-B1 | 7-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS, METHODS OF USING AND MAKING THE SAME | TREVENA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-4086249-A2 | 6-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS, METHODS OF USING AND MAKING THE SAME | Trevena, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |
| CN-114014859-A | Triazole indolol compound and synthesis method thereof | 绍兴文理学院 | 2022-02-08 | — | — | CN | disclosed |
| US-11077090-B2 | Compounds and compositions and uses thereof | SUNOVION PHARMACEUTICALS INC. (MA) | 2021-08-03 | — | — | US | disclosed |
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |
| US-10246436-B2 | 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same | TREVENA, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-7425653-B2 | Aromatic amine derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| US-7425653-B2 | Aromatic amine derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| US-20070236137-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-10-11 | — | — | US | disclosed |
| US-20070236137-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1626714-B1 | DIARYL UREAS FOR DISEASES MEDIATED BY PDGFR | BAYER PHARMACEUTICALS CORP (US) | 2007-07-04 | — | — | EP | disclosed |
| EP-1792893-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2007058602-A2 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER’S DISEASE, NEURODEGENERATION AND DEMENTIA. | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |
| US-5395827-A | Analgesic, anticonvulsant, antiepileptic and anxiolytic agents | GUILFORD PHARMACEUTICALS INC. (US) | 1995-03-07 | — | — | US | disclosed |
| US-5364876-A | Tranquilizers, analgesics, learning enhancement | GUILFORD PHARMACEUTICALS INC. (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993005772-A1 | φ-[2-(PHOSPHONOALKYL)PHENYL]-2-AMINOALKANOIC ACIDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070236137-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | TYR, MAOA, MAOB | PIK3CD 3786/4885METAP1 2326/4885ADRA2A 82/4885 |
| US-11077090-B2 | Compounds and compositions and uses thereof | ACHE, CHAT, MAOB | PIK3CD 3094/4885METAP1 2074/4885ADRA2A 1230/4885 |
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | ULK1, ULK2, ULK3 | PIK3CD 425/4885METAP1 3632/4885ADRA2A 3895/4885 |
| US-10246436-B2 | 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same | OPRD1, OPRM1, OPRK1 | PIK3CD 1137/4885METAP1 2886/4885ADRA2A 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.