Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940077 | 0.87 | KMT2A (0.67) | KMT2AMEN1ITPR1FAAHHPGD | |
| SCHEMBL31713966 | 0.86 | KMT2A (0.66) | KMT2AMEN1ITPR1FAAHHPGD | |
| SCHEMBL21615671 | 0.83 | EPHX2 (0.51) | KMT2AMEN1FAAHMTNR1ATRPV1 | |
| SCHEMBL2009382 | 0.81 | KMT2A (0.50) | KMT2AMEN1ITPR1FAAHHPGD | |
| SCHEMBL19927181 | 0.81 | KMT2A (0.49) | KMT2AMEN1ITPR1FAAHHPGD | |
| SCHEMBL14940250 | 0.81 | KMT2A (0.53) | KMT2AMEN1FAAHHPGDKDM4E | |
| SCHEMBL19785408 | 0.80 | KMT2A (0.50) | KMT2AMEN1ITPR1FAAHHPGD | |
| SCHEMBL28136251 | 0.79 | KMT2A (0.47) | KMT2AMEN1ITPR1FAAHHPGD | |
| SCHEMBL1801575 | 0.78 | KMT2A (0.50) | KMT2AMEN1ITPR1FAAHHPGD | |
| SCHEMBL12571772 | 0.78 | KMT2A (0.50) | KMT2AMEN1FAAHHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660967-A | Process for the cycloaddition of a hetero(aryl) 1,3-dipole compound with a (hetero)cycloalkyne | 西纳福克斯股份有限公司 | 2017-05-10 | — | — | CN | disclosed |