SCHEMBL2009382

SCHEMBL2009382

O=C(CCl)NCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
FAAH O00519 1/20 0.43
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 4/20 0.42
HPGD P15428 2/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
POLB P06746 2/20 0.40
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
CYP2D6 P10635 1/20 0.40
HSD17B10 Q99714 1/20 0.40
F10 P00742 1/20 0.39
LMNA P02545 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14940250 0.88 KMT2A (0.53) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL21971924 0.87 CA1 (0.38) KMT2AMEN1FAAHALDH1A1HTT
SCHEMBL1801575 0.85 KMT2A (0.50) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL12571772 0.85 KMT2A (0.50) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL20422761 0.84 KMT2A (0.49) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL24700650 0.82 KMT2A (0.48) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL14940077 0.82 KMT2A (0.67) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL27931462 0.81 ALDH1A1 (0.55) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL19785408 0.81 KMT2A (0.50) KMT2AMEN1FAAHALDH1A1KDM4E
SCHEMBL12571808 0.81 KMT2A (0.47) KMT2AMEN1FAAHALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370950-B2 Surface-modified inorganic nitride, composition, thermally conductive material, and device with thermally conductive layer FUJIFILM CORPORATION (JP) 2022-06-28 US disclosed
EP-3653573-A1 SURFACE-MODIFIED INORGANIC NITRIDE, COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, DEVICE PROVIDED WITH THERMALLY CONDUCTIVE LAYER FUJIFILM Corporation (JP) 2020-05-20 EP disclosed
US-20200140738-A1 SURFACE-MODIFIED INORGANIC NITRIDE, COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2020-05-07 US disclosed
US-7964721-B2 A mercury preferential fluorescence detectors used for detecting mercury ions; microfulidic chemical analysis CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) 2011-06-21 US disclosed
US-7964721-B2 A mercury preferential fluorescence detectors used for detecting mercury ions; microfulidic chemical analysis CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) 2011-06-21 US disclosed
US-20080255346-A1 Ratiometric fluorescent chemosensor for selective detection of Hg (II) ions CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) 2008-10-16 US disclosed
US-20080255346-A1 Ratiometric fluorescent chemosensor for selective detection of Hg (II) ions CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255346-A1 Ratiometric fluorescent chemosensor for selective detection of Hg (II) ions TRPA1, TRPM2, GRIA1 KMT2A 3237/4885MEN1 734/4885FAAH 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.