4-Nitrobenzoyl Chloride

4-Nitrobenzoyl Chloride

SCHEMBL28136998

O=C(Cl)c1ccc([N+](=O)[O-])cc1.[O-][S+](Cl)Cl

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.85
CES1 P23141 2/20 0.59
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
TSHR P16473 2/20 0.55
MAPK1 P28482 2/20 0.55
CES2 O00748 1/20 0.52
SRD5A2 P31213 1/20 0.52
GSK3B P49841 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
POLB P06746 2/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitrobenzoyl Chloride SCHEMBL28873526 0.92 ALDH1A1 (1.00) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL43141 0.92 ALDH1A1 (1.00) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL5400755 0.90 ALDH1A1 (0.96) ALDH1A1CES1CA1CA2TDP1
SCHEMBL3032088 0.86 ALDH1A1 (0.88) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL27787602 0.86 ALDH1A1 (0.88) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL9129925 0.86 ALDH1A1 (0.88) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL9613734 0.85 ALDH1A1 (0.85) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL28780944 0.85 ALDH1A1 (0.85) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoic Acid SCHEMBL28796437 0.85 TDP1 (0.81) ALDH1A1CES1CA1CA2TDP1
SCHEMBL7785604 0.81 ALDH1A1 (0.79) ALDH1A1CES1CA1CA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106866422-A The process for refining of paranitrobenzoyl chloride 山东凯盛新材料有限公司 2017-06-20 CN disclosed
CN-106866423-A The aftertreatment technology of paranitrobenzoyl chloride 山东凯盛新材料有限公司 2017-06-20 CN disclosed