4-Nitrobenzoyl Chloride

4-Nitrobenzoyl Chloride

SCHEMBL43141

O=C(Cl)c1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
CES1 P23141 2/20 0.68
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
TSHR P16473 2/20 0.63
MAPK1 P28482 2/20 0.63
CES2 O00748 1/20 0.59
SRD5A2 P31213 1/20 0.59
GSK3B P49841 1/20 0.57
LMNA P02545 1/20 0.57
GAA P10253 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.55
POLB P06746 2/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitrobenzoyl Chloride SCHEMBL28873526 1.00 ALDH1A1 (1.00) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL5400755 0.98 ALDH1A1 (0.96) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL9129925 0.94 ALDH1A1 (0.88) ALDH1A1CES1CA1CA2TDP1
SCHEMBL3032088 0.94 ALDH1A1 (0.88) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL27787602 0.94 ALDH1A1 (0.88) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL28136998 0.92 ALDH1A1 (0.85) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL28780944 0.92 ALDH1A1 (0.85) ALDH1A1CES1CA1CA2TDP1
4-Nitrobenzoyl Chloride SCHEMBL9613734 0.92 ALDH1A1 (0.85) ALDH1A1CES1CA1CA2TDP1
SCHEMBL6298519 0.89 ALDH1A1 (0.79) ALDH1A1CES1CA1CA2TDP1
SCHEMBL4687395 0.89 ALDH1A1 (0.79) ALDH1A1CES1CA1CA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9568 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121591615-B Memantine derivative and synthesis method and application thereof Shandong Xinhua Pharmaceutical Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-121591614-B Adamantane derivative and synthesis method and application thereof Shandong Xinhua Pharmaceutical Co.,Ltd. (CN) 2026-05-26 CN claimed
US-20250255813-A1 TRIPTOLIDE LIGNOCERATE, LIPOSOME THEREOF AND PREPARATION METHOD THEREFOR SHANGHAI WEI ER BIOPHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2025-08-14 US claimed
CN-116284203-B Tanshinone IIA C-1 position esterified derivative and preparation method and application thereof 郑州大学 2025-06-10 CN claimed
CN-120126936-A Electrolyte of aluminum electrolytic capacitor and preparation method thereof 东莞市鸿安电子有限公司 2025-06-10 CN claimed
CN-118851927-B Preparation process of dimethylcaline hydrochloride 海南三帝制药有限公司 2025-05-30 CN claimed
CN-119899686-A Method for improving ageing resistance of asphalt through halogenation, aryl acylation and alkylation reaction 西安交通大学 2025-04-29 CN claimed
CN-119868641-A Self-assembled calcium phosphate microsphere with high specific surface area and preparation method thereof 成都贝雅医疗科技有限公司 2025-04-25 CN claimed
CN-115836048-B Synthesis of N- (2, 4-dinitrophenyl) -4-nitrobenzamide (TNBA) using solid acid catalyst 杜邦安全与建筑公司 2025-04-18 CN claimed
CN-116874839-B Preparation method of polyimide film with low thermal expansion coefficient for copper-clad plate 黄山金石木塑料科技有限公司 2025-04-18 CN claimed
EP-0103184-A2 Activation of biocompatible terpolymers with biologicals whose binding complements are pathological effectors Kanegafuchi Chemical Industry Co., Ltd. (JP) 1984-03-21 EP claimed
US-4343871-A GROUP IA METAL ANODE AND CATHODE FORMED OF ORGANIC COMPOUND HAVINGPI-ELECTRON CONJUGATED SYSTEM NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1982-08-10 US claimed
US-4325946-A ANTITUMOR AGENTS FARMITALIA CARLO ERBA S.P.A. (IT) 1982-04-20 US claimed
EP-0001246-B1 PREPARATION OF 2-(3'- OR 4'-AMINOPHENYL)-5(OR 6)-AMINOBENZIMIDAZOLES CASSELLA Aktiengesellschaft (DE) 1981-02-25 EP claimed
US-4142853-A BENZOYLATION SHIKIBO LIMITED (JP) 1979-03-06 US claimed
US-4137399-A Method of preparing functionalized celluloses DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-01-30 US claimed
US-4113431-A CELLULOSE REACTED WITH A BENZOYLATING AGENT SHIKIBO LIMITED (JP) 1978-09-12 US claimed
US-4046882-A Isolation of utero-evacuant substances from plant extracts ORTHO PHARMACEUTICAL CORPORATION (US) 1977-09-06 US claimed
US-3998844-A WITH AN AROYL CHLORIDE TO FORM A 5-AROYL-1-ALKYLPYRROLE-2-ACETIC ACID DERIVATIVE MCNEIL LABORATORIES, INCORPORATED (US) 1976-12-27 US claimed
US-3989685-A FROM PENICILLIN-1-OXIDE SHINOGI & CO., LTD. (JA) 1976-11-02 US claimed