Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28328509 | 0.81 | LCK (0.44) | LCKSRCKDRLIMK1LIMK2 | |
| SCHEMBL17197477 | 0.78 | QDPR (0.52) | LCKSRCKDRLIMK1LIMK2 | |
| SCHEMBL5783658 | 0.74 | HTT (0.59) | KMT2ANPC1RAB9ATACR3CA1 | |
| SCHEMBL9524227 | 0.74 | NPC1 (0.56) | LCKSRCKDRLIMK1LIMK2 | |
| SCHEMBL17197481 | 0.73 | HRH3 (0.49) | LCKSRCKDRLIMK1LIMK2 | |
| SCHEMBL17197366 | 0.73 | NAMPT (0.51) | LCKSRCKDRLIMK1LIMK2 | |
| SCHEMBL29950865 | 0.72 | NPC1 (0.53) | KMT2ANPC1RAB9ATACR3CA1 | |
| SCHEMBL10163089 | 0.71 | KMT2A (0.58) | KMT2ANPC1RAB9ATACR3CA1 | |
| SCHEMBL9524084 | 0.70 | LMNA (0.71) | KMT2AALDH1A1MEN1HTT | |
| SCHEMBL10929623 | 0.70 | KMT2A (0.54) | KMT2ANPC1RAB9ATACR3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536503-A | Tyrosine kinase inhibitor and uses thereof | 山东轩竹医药科技有限公司 | 2017-03-22 | — | — | CN | disclosed |