Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18336393 | 0.80 | TNIK (0.38) | TNIKBACE1TBK1IKBKEFABP4 | |
| SCHEMBL20424077 | 0.73 | KDM4E (0.37) | — | |
| SCHEMBL20436823 | 0.71 | KMT2A (0.51) | ALDH1A1HSD17B10 | |
| SCHEMBL18337002 | 0.69 | FABP4 (0.32) | BACE1IRAK4FABP4FABP5MAPT | |
| SCHEMBL4832820 | 0.69 | — | — | |
| SCHEMBL28323154 | 0.68 | PIK3CG (0.37) | BACE1IRAK4FABP4FABP5MAPT | |
| SCHEMBL19385549 | 0.68 | NNMT (0.38) | ALDH1A1LMNAACHE | |
| SCHEMBL8002161 | 0.68 | KDM4E (0.49) | BACE1IRAK4MAPTALDH1A1 | |
| SCHEMBL18336097 | 0.68 | FABP4 (0.33) | IRAK4FABP4FABP5ALOX15 | |
| SCHEMBL18336602 | 0.67 | HSP90AB1 (0.33) | BACE1FABP4FABP5MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661017-A | novel bicyclic or tricyclic heterocyclic compounds | 田边三菱制药株式会社 | 2017-05-10 | — | — | CN | disclosed |