Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820306 | 0.82 | LMNA (0.39) | LMNAKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL18337153 | 0.81 | LMNA (0.41) | LMNAKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL3731513 | 0.78 | LMNA (0.43) | LMNAKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL2305832 | 0.75 | PPARD (0.35) | LMNAKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL30688636 | 0.74 | LMNA (0.47) | LMNAKDM4EHSD17B10MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL5013627 | 0.74 | PPARD (0.34) | LMNAKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL27558227 | 0.74 | NOS1 (0.48) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL2745274 | 0.74 | IKBKB (0.35) | LMNAKDM4EALDH1A1IKBKBLIMK1 | |
| SCHEMBL2894541 | 0.74 | PDPK1 (0.33) | LMNAKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL10431346 | 0.72 | F2 (0.33) | KDM4EMAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661017-B | Bicyclic or tricyclic heterocyclic compounds | 田边三菱制药株式会社 | 2019-09-24 | — | — | CN | disclosed |
| CN-106661017-A | novel bicyclic or tricyclic heterocyclic compounds | 田边三菱制药株式会社 | 2017-05-10 | — | — | CN | disclosed |