SCHEMBL28138

SCHEMBL28138

CCCCCCCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
LMNA P02545 3/20 0.42
DNM1 Q05193 5/20 0.33
ALDH1A1 P00352 3/20 0.33
LPAR2 Q9HBW0 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232060 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL818646 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL26406 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL14760231 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL26538 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
Octane SCHEMBL18660174 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL16538101 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL6534000 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL21456807 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL25767 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES CHAN, Hardy Wai Hong (TW) 2026-01-01 US claimed
CN-120154535-A Ionic liquid anticarious paint with antibacterial and mineralization promoting functions and preparation method thereof 中国人民解放军空军军医大学 2025-06-17 CN claimed
CN-119331433-B High-dispersibility phthalocyanine pigment and preparation method thereof 淄博福颜化工集团有限公司 2025-03-21 CN claimed
CN-119331433-A High-dispersibility phthalocyanine pigment and preparation method thereof 淄博福颜化工集团有限公司 2025-01-21 CN claimed
WO-2024263122-A1 SUPERHYDROPHOBIC AND SUPEROLEOPHILIC COMPOSITE SPONGE MATERIAL AND THE PRODUCTION METHOD THEREOF AKDENIZ UNIVERSITESI (TR) 2024-12-26 WO claimed
US-20240352315-A1 METHODS AND COMPOSITIONS FOR ENHANCED DISPERSION OF PHOSPHOR IN A POLYMERIC MATRIX BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-10-24 US claimed
EP-4358119-A2 IMPROVED SELF-ASSEMBLED MONOLAYER BLOCKING WITH INTERMITTENT AIR-WATER EXPOSURE Applied Materials, Inc. (US) 2024-04-24 EP claimed
US-11903767-B2 Composite tissue markers detectable via multiple detection modalities VIEW POINT MEDICAL, INC. (US) 2024-02-20 US claimed
US-11882992-B2 Composite tissue markers detectable via multiple detection modalities including radiopaque element VIEW POINT MEDICAL, INC. (US) 2024-01-30 US claimed
CN-112239209-B Drug delivery via pore-modified mesoporous silica nanoparticles 奈力生医股份有限公司 2024-01-12 CN claimed
EP-0748359-B1 IMPROVED PROCESSIBILITY AND LACING RESISTANCE WHEN SILANIZED PIGMENTS ARE INCORPORATED IN POLYMERS DU PONT (US) 1999-08-18 EP claimed
EP-0748362-B1 PROCESS FOR PREPARING SILANIZED TiO 2 PIGMENTS USING A MEDIA MILL DU PONT (US) 1997-12-29 EP claimed
US-5635326-A COLORANT-CONTAINING PARTICULATE RESIN AND TITANIUM OXIDE AND AN ALKYL TITANATED TREATED WITH A SILANE-TYPE ORGANIC COMPOUND; SHARPNESS; ANTIFOGGING AGENTS; DURABILITY; COPIERS; ELECTROPHOTOGRAPHY CANON KABUSHIKI KAISHA (JP) 1997-06-03 US claimed
US-5607994-A POLYETHYLENE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-04 US claimed
EP-0748362-A1 PROCESS FOR PREPARING SILANIZED TiO 2 PIGMENTS USING A MEDIA MILL E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-18 EP claimed
EP-0748359-A1 IMPROVED PROCESSIBILITY AND LACING RESISTANCE WHEN SILANIZED PIGMENTS ARE INCORPORATED IN POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-18 EP claimed
US-5501732-A Process for preparing silanized TiO2 pigments using a media mill E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-26 US claimed
EP-0674237-A1 Electrostatic image-developing toner, fine powdery titanium oxide, and hydrophobic fine powdery titanium oxide CANON KABUSHIKI KAISHA (JP) 1995-09-27 EP claimed
WO-1995023194-A1 PROCESS FOR PREPARING SILANIZED TiO2 PIGMENTS USING A MEDIA MILL E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-31 WO claimed
WO-1995023192-A1 IMPROVED PROCESSIBILITY AND LACING RESISTANCE WHEN SILANIZED PIGMENTS ARE INCORPORATED IN POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES AQP4, ABCB1, SRMS TSHR 3081/4885THRB 3746/4885LMNA 1004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.