SCHEMBL818646

SCHEMBL818646

CCCCCCCCCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
LMNA P02545 3/20 0.42
DNM1 Q05193 5/20 0.33
ALDH1A1 P00352 3/20 0.33
LPAR2 Q9HBW0 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232060 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL28138 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL26406 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL14760231 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL26538 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
Octane SCHEMBL18660174 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL16538101 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL6534000 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL21456807 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL25767 1.00 TSHR (0.42) TSHRTHRBLMNADNM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES CHAN, Hardy Wai Hong (TW) 2026-01-01 US claimed
US-12448582-B2 Methods of improving the performance of combustion engine after-treatment devices AFTON CHEMICAL CORPORATION (US) 2025-10-21 US claimed
CN-119331433-B High-dispersibility phthalocyanine pigment and preparation method thereof 淄博福颜化工集团有限公司 2025-03-21 CN claimed
CN-119331433-A High-dispersibility phthalocyanine pigment and preparation method thereof 淄博福颜化工集团有限公司 2025-01-21 CN claimed
WO-2024263122-A1 SUPERHYDROPHOBIC AND SUPEROLEOPHILIC COMPOSITE SPONGE MATERIAL AND THE PRODUCTION METHOD THEREOF AKDENIZ UNIVERSITESI (TR) 2024-12-26 WO claimed
CN-118547402-B Para-aramid spinning oil and preparation method thereof 烟台锐泽化学品有限公司 2024-11-01 CN claimed
US-20240336862-A1 METHODS OF IMPROVING THE PERFORMANCE OF COMBUSTION ENGINE AFTER-TREATMENT DEVICES AFTON CHEMICAL CORPORATION 2024-10-10 US claimed
EP-3858954-B1 LUBRICANT FORMULATIONS WITH SILICON-CONTAINING COMPOUNDS AFTON CHEMICAL CORP (US) 2024-10-09 EP claimed
CN-118547402-A Para-aramid spinning oil and preparation method thereof 烟台锐泽化学品有限公司 2024-08-27 CN claimed
EP-4358119-A2 IMPROVED SELF-ASSEMBLED MONOLAYER BLOCKING WITH INTERMITTENT AIR-WATER EXPOSURE Applied Materials, Inc. (US) 2024-04-24 EP claimed
CN-104053701-A Composition of olefinically functionalsied siloxane oligomers based on alkoxy silanes EVONIK DEGUSSA GMBH 2014-09-17 CN claimed
CN-104053699-A Low chlorine compositions of olefin-functionalized siloxane oligomers based on alkoxysilanes EVONIK DEGUSSA GMBH 2014-09-17 CN claimed
WO-2013076032-A1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2013-05-30 WO claimed
WO-2013076036-A1 COMPOSITION OF OLEFINICALLY FUNCTIONALSIED SILOXANE OLIGOMERS BASED ON ALKOXY SILANES EVONIK DEGUSSA GMBH (DE) 2013-05-30 WO claimed
WO-2013076035-A1 MIXTURES, PARTICULARLY LOW IN VOLATILE ORGANIC COMPOUNDS (VOC), OF OLEFINICALLY FUNTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXY SILANES EVONIK DEGUSSA GMBH (DE) 2013-05-30 WO claimed
US-8378008-B2 Surface-modified non-halogenated mineral fillers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-02-19 US claimed
US-20110009545-A1 SURFACE-MODIFIED NON-HALOGENATED MINERAL FILLERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-13 US claimed
US-20100122711-A1 WET CLEAN METHOD FOR SEMICONDUCTOR DEVICE FABRICATION PROCESSES ADVANCED MICRO DEVICES, INC. (US) 2010-05-20 US claimed
CN-1243058-C Polyaminoester /molecular sieve composite material and its preparation method UNIV TAIYUAN TECHNOLOGY (CN) 2006-02-22 CN claimed
CN-1546568-A Polyaminoester /molecular sieve composite material and its preparation method 太原理工大学 2004-11-17 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES AQP4, ABCB1, SRMS TSHR 3081/4885THRB 3746/4885LMNA 1004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.