Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709 | 0.92 | — | — | |
| SCHEMBL4916223 | 0.92 | LMNA (0.61) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| SCHEMBL20852333 | 0.92 | LMNA (0.61) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Nitrogen SCHEMBL11864887 | 0.90 | LMNA (0.55) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Ethane SCHEMBL29007244 | 0.90 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| SCHEMBL9573532 | 0.90 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| SCHEMBL29961278 | 0.90 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Ammonia Solution, Strong SCHEMBL8429752 | 0.90 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Water SCHEMBL9462188 | 0.90 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Iodide SCHEMBL17710408 | 0.90 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632409-B | A kind of Ah flutter'ssing gossypol derivative and preparation method thereof and antitumor and immunoregulatory application | 江苏度未生物工程科技有限公司 | 2018-08-28 | — | — | CN | disclosed |
| CN-106632409-A | Apogossypol derivatives and preparation method thereof, and application of apogossypol derivatives in antitumor and immunoregulation | 武汉大学 | 2017-05-10 | — | — | CN | disclosed |