Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20852333 | 0.97 | LMNA (0.61) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| SCHEMBL7709 | 0.97 | — | — | |
| SCHEMBL4916223 | 0.97 | LMNA (0.61) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Ethane SCHEMBL29007244 | 0.94 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| SCHEMBL9573532 | 0.94 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| SCHEMBL29961278 | 0.94 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Water SCHEMBL9462188 | 0.94 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Iodide SCHEMBL17710408 | 0.94 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| SCHEMBL7707049 | 0.94 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR | |
| Bromide SCHEMBL17710440 | 0.94 | LMNA (0.59) | LMNAMAPTALDH1A1ADRA2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | Gacter Inc. (US) | 2023-09-14 | — | — | US | claimed |
| CN-103351907-B | Non-metallic antiknock agent and preparation method thereof | YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD | 2015-07-08 | — | — | CN | claimed |
| EP-0144980-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 3-AMINOCARBOXYLIC ACIDS (ESTERS) | LONZA AG (CH) | 1989-07-12 | — | — | EP | claimed |
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | Gacter Inc. (US) | 2023-09-14 | — | — | US | disclosed |
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | Gacter Inc. (US) | 2023-09-14 | — | — | US | disclosed |
| CN-113437222-A | Lead-free tin-based perovskite thin film, lead-free tin-based perovskite solar cell and preparation method of lead-free tin-based perovskite solar cell | 西北工业大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-105669970-B | Polyamide-based expandable flame retardant carbon forming agent and its preparation method and application of the main chain containing piperazine structure | 四川大学 | 2018-11-02 | — | — | CN | disclosed |
| EP-3388419-A1 | GLI1 INHIBITORS AND USES THEREOF | Leadiant Biosciences SA (CH) | 2018-10-17 | — | — | EP | disclosed |
| CN-103351907-B | Non-metallic antiknock agent and preparation method thereof | YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD | 2015-07-08 | — | — | CN | disclosed |
| US-20150157581-A1 | BENZYLAMINE CONTAINING COMPOSITIONS AND METHODS FOR APPETITE SUPPRESSION | ZIJA INTERNATIONAL, INC. (US) | 2015-06-11 | — | — | US | disclosed |
| WO-2014130398-A1 | BENZYLAMINE CONTAINING COMPOSITIONS AND METHODS FOR APPETITE SUPPRESSION | ZIJA INTERNATIONAL, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| US-20140235729-A1 | BENZYLAMINE CONTAINING COMPOSITIONS AND METHODS FOR APPETITE SUPPRESSION | ZIJA INTERNATIONAL, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| CN-103351907-A | Non-metallic antiknock agent and preparation method thereof | YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD | 2013-10-16 | — | — | CN | disclosed |
| CN-1894283-B | Reactive polysaccharide derivates, their preparation and their use | CIBA SC HOLDING AG | 2012-07-04 | — | — | CN | disclosed |
| CN-1894283-A | Reactive polysaccharide derivates, their preparation and their use | CIBA SC HOLDING AG (CH) | 2007-01-10 | — | — | CN | disclosed |
| US-6001835-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150157581-A1 | BENZYLAMINE CONTAINING COMPOSITIONS AND METHODS FOR APPETITE SUPPRESSION | PNMT, BRS3, DBH | LMNA 3653/4885MAPT 4255/4885ALDH1A1 2645/4885 |
| US-20140235729-A1 | BENZYLAMINE CONTAINING COMPOSITIONS AND METHODS FOR APPETITE SUPPRESSION | PNMT, BRS3, DBH | LMNA 3653/4885MAPT 4255/4885ALDH1A1 2645/4885 |
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | NOS1, NOS3, NOS2 | LMNA 3745/4885MAPT 2248/4885ALDH1A1 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.