Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL28138276 | 0.90 | MYC (0.31) | MYCPTPN2PTPN1 | |
| SCHEMBL28331891 | 0.86 | PTPN2 (0.38) | LMNAPTPN2PTPN1 | |
| SCHEMBL28138290 | 0.80 | PTPN2 (0.34) | PTPN2PTPN1 | |
| SCHEMBL28138284 | 0.80 | PTPN2 (0.34) | PTPN2PTPN1 | |
| SCHEMBL28138830 | 0.78 | KDM4E (0.30) | — | |
| SCHEMBL9362569 | 0.76 | KDM4E (0.44) | LMNAMYCPTPN2PTPN1 | |
| SCHEMBL28138889 | 0.75 | BRD4 (0.38) | LMNA | |
| SCHEMBL26416381 | 0.67 | PTPN2 (0.42) | LMNAPTPN2PTPN1 | |
| SCHEMBL28285820 | 0.66 | BCHE (0.36) | LMNA | |
| SCHEMBL5398797 | 0.65 | MEN1 (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573896-B | Fluoroalkylating agents | KUMIAI CHEMICAL INDUSTRY CO.,LTD. (JP) | 2019-11-01 | — | — | CN | disclosed |
| CN-106573896-A | Fluoroalkylating agents | 庵原化学工业株式会社 | 2017-04-19 | — | — | CN | disclosed |