Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049325 | 0.79 | GAA (0.62) | KDM4EALDH1A1GAAHPGDALOX12 | |
| SCHEMBL30353863 | 0.79 | GAA (0.62) | KDM4EALDH1A1GAAHPGDALOX12 | |
| Iodide SCHEMBL9134484 | 0.77 | GAA (0.60) | KDM4EALDH1A1GAAHPGDALOX12 | |
| SCHEMBL28285820 | 0.77 | BCHE (0.36) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL5398797 | 0.76 | MEN1 (0.44) | KDM4EGAALMNAMAPT | |
| SCHEMBL28138292 | 0.76 | LMNA (0.32) | LMNAMYCPTPN2PTPN1 | |
| SCHEMBL10422548 | 0.73 | MYC (0.33) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL17066696 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAHPGDALOX12 | |
| SCHEMBL196642 | 0.71 | GAA (0.47) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL29414570 | 0.71 | GAA (0.47) | KDM4EALDH1A1GAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318294-B1 | Dimeric and trimeric cationic dyes | NIPPON CHEMICAL WORKS (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5125930-A | Polymeric cationic dyes including a quaternized pyridinium group | NIPPON CHEMICAL WORKS CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |