Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599815 | 0.82 | NOTUM (0.48) | MAOAMAOBNOTUMKMT2AMEN1 | |
| SCHEMBL29390912 | 0.73 | MAOA (1.00) | MAOAMAOBNOTUMHTR1AADRA2A | |
| SCHEMBL98108 | 0.73 | MAOA (1.00) | MAOAMAOBNOTUMHTR1AADRA2A | |
| SCHEMBL56072 | 0.73 | MAOA (0.54) | MAOAMAOBNOTUMKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL23501375 | 0.71 | MAOA (1.00) | MAOAMAOBNOTUMHTR1AADRA2A | |
| SCHEMBL9697633 | 0.71 | MAOA (0.58) | MAOAMAOBNOTUMKMT2AMEN1 | |
| SCHEMBL302485 | 0.71 | MAOA (0.58) | MAOAMAOBNOTUMKMT2AMEN1 | |
| SCHEMBL15256256 | 0.71 | MAOA (0.58) | MAOAMAOBNOTUMKMT2AMEN1 | |
| SCHEMBL98107 | 0.71 | MAOA (0.58) | MAOAMAOBNOTUMKMT2AMEN1 | |
| SCHEMBL14886174 | 0.71 | MAOA (0.58) | MAOAMAOBNOTUMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106581013-B | A kind of purposes of salicylic acid compounds in preparation neurodegenerative disease drug | 南阳师范学院 | 2019-08-06 | — | — | CN | disclosed |
| CN-106581013-A | Application of salicylic compounds in preparation of neurodegenerative disease drugs | 南阳师范学院 | 2017-04-26 | — | — | CN | disclosed |