Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708259 | 0.91 | REN (0.59) | RENCYP3A4KCNH2 | |
| SCHEMBL2814538 | 0.89 | REN (0.57) | RENCYP3A4KCNH2 | |
| SCHEMBL696074 | 0.89 | REN (0.63) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL9959187 | 0.88 | REN (0.57) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL700661 | 0.87 | REN (0.77) | RENCYP3A4 | |
| SCHEMBL696533 | 0.85 | REN (0.58) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL700945 | 0.84 | REN (0.57) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL708306 | 0.84 | REN (0.60) | RENCYP3A4 | |
| SCHEMBL2818546 | 0.84 | REN (0.60) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL698976 | 0.84 | REN (0.60) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122580-A2 | NOVEL COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2010-10-28 | — | — | WO | claimed |